Helmholtz Research Field: Information

Institute of Active Polymers

Gossen-et-al 2020

Introducing mRNA in human macrophages with high efficiency and few side effects

Study of the Institute of Biomaterial Science published today in Scientific Reports
Frank Gu Vorschau

New Year’s Lecture 2020 from the Graduate School for Macromolecular Bioscience

Welcome, Professor Frank Gu.
Climbing like the Clematis: GrowBot to imitate climbing plants

Climbing like the Clematis: GrowBot to imitate climbing plants

Scientists from the Institute develop artificial muscles for new EU project.  More

Drug delivery expert Professor Kinam Park presents guest lecture

Drug delivery expert Professor Kinam Park presents guest lecture

On the 14th May 2019, the Helmholtz Graduate School for Macromolecular Bioscience welcomed Prof. Park  More

Fundamental research at the Institute of Active Polymers is focused on multifunctional, polymer-based materials for applications in Regenerative Medicine. The vision for tomorrow´s medicine is spectacular but challenging at the same time: to enable the regeneration of diseased or injured tissue, cells and complex organs or to at least partially restore their function. Novel biomaterials are providing a basis and constitute a key technology for induced auto-regeneration, especially in combination with bioactive molecules. Furthermore, they have a high application potential as support systems for somatic cell therapy and tissue engineering.

The research of the Institute, headed by Prof. Dr. Andreas Lendlein, is contributing to solve problems arising with the socio-economical change of our society: The progressing life expectancy as well as changing everyday physical strains are leading to an increase of degenerative, chronic inflammatory, and age-related diseases whose symptoms can often only be alleviated yet not cured. The development of regenerative therapies aims at curative treatment options enabling the restoration of impaired functions by endogenous healing- and regeneration processes or biological replacement. Innovative biomaterials open up entirely new medical possibilities as implants or drug releasing systems with properties and functions tailored specifically to the demands of each application.

Latest Publications

Publication appeared in Journal of Controlled Release:

Oligodepsipeptide (nano)carriers: Computational design and analysis of enhanced drug loading

Graphical abstract 2019 J. Controlled Release Brunnaci Oligodepsipeptide

An approach to increase the drug loading of a degradable drug delivery matrix through was investigated through computer simulation. Strengthening the intermolecular interactions between a drug (DXM, dexamethasone) and a novel matrix (OBMD) was found to increase drug loading compared to a standard matrix (PLGA).

Authors: Nadia Brunacci, Axel T. Neffe, Christian Wischke, Toufik Naolou, Ulrich Nöchel, Andreas Lendlein.

To News Article

To Publication

Prof. Dr. Andreas Lendlein

Prof. Dr. Andreas Lendlein

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Helmholtz Graduate School Macromolecular Bioscience

The newly established Helmholtz Graduate School offers a structured and application oriented PhD Program in Biomaterial Research and Macromolecular Bioscience.

Contact for PhD students
Prof. Dr. Nan Ma

Prof. Dr. Nan Ma
Speaker Graduate School

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BCRT - Interdisciplinary Translational Center

At the BCRT we develop methods and tools for Regenerative Medicine based on biomaterials and drug delivery systems together with the Charité, Universitätsmedizin Berlin.

Campus Teltow

HZG Institute of Biomaterial Science

Kantstraße 55, D-14153 Teltow

Phone: +49 (0)3328 352-0
Email contact

Campus Virchow-Klinikum

Charité, Universitäts-medizin Berlin

Augustenburger Pl. 1, D-13353 Berlin

Phone: +49 (0)30 450 539-400
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Helmholtz Portfolio Topic
„Technology and Medicine"

Within this Portfolio Topic we explore the connections of technology driven approaches in health research and their relevance for medical diagnostics and therapies.